CYCLOPHOSPHAMIDE Meaning and
Definition
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Cyclophosphamide is a chemical compound that belongs to the class of alkylating agents, commonly used as a chemotherapy drug in the treatment of various types of cancers. It is an organic nitrogen mustard prodrug that requires metabolic activation in the liver to exert its cytotoxic effects.
The compound is primarily used in the treatment of solid tumors, hematological malignancies such as leukemia and lymphoma, and as an immunosuppressive agent in certain autoimmune disorders. Cyclophosphamide works by interfering with the process of DNA replication and cell division, thereby inhibiting the growth of cancerous cells.
As a prodrug, cyclophosphamide is converted into its active form called 4-hydroxycyclophosphamide, which is further metabolized into two main active cytotoxic compounds: phosphoramide mustard and acrolein. These metabolites have the ability to damage DNA and inhibit cellular processes necessary for tumor growth.
The administration of cyclophosphamide is through intravenous or oral routes, and its usage may be accompanied by other chemotherapeutic agents to enhance its effectiveness. Despite being an effective chemotherapy drug, cyclophosphamide has potential side effects such as bone marrow suppression, gastrointestinal disturbances, hair loss, and an increased risk of infection.
In summary, cyclophosphamide is an alkylating agent used in cancer treatment that interferes with DNA replication and cell division. It is converted into active metabolites that exert cytotoxic effects on cancerous cells, playing a crucial role in the management of different types of cancers.
Common Misspellings for CYCLOPHOSPHAMIDE
- xyclophosphamide
- vyclophosphamide
- fyclophosphamide
- dyclophosphamide
- ctclophosphamide
- cgclophosphamide
- chclophosphamide
- cuclophosphamide
- c7clophosphamide
- c6clophosphamide
- cyxlophosphamide
- cyvlophosphamide
- cyflophosphamide
- cydlophosphamide
- cyckophosphamide
- cycpophosphamide
- cycoophosphamide
- cycliphosphamide
- cyclkphosphamide
- cycllphosphamide
Etymology of CYCLOPHOSPHAMIDE
The word "Cyclophosphamide" is derived from a combination of two parts: "Cyclo-" and "-phosphamide".
"Cyclo-" comes from the Greek word "kyklos", meaning "circle" or "ring". In this context, it refers to the cyclic structure of the chemical compound.
The term "-phosphamide" combines the suffix "-amide" with "phosphor-". "-Amide" generally refers to a compound containing a carbonyl group (C=O) bonded to an amino group (NH2). "Phosphor-" refers to phosphorus, an element widely used in organic chemistry. In this case, it signifies a chemical compound containing a phosphate group (PO3).
Therefore, "Cyclophosphamide" refers to a cyclic chemical compound that contains a carbonyl group and a phosphate group.
Idioms with the word CYCLOPHOSPHAMIDE
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