ANK REPEAT Meaning and
Definition
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ANK repeat refers to a specific type of protein structural motif found in various proteins. The term "ANK" stands for ankyrin, which is a protein family known for their crucial roles in mediating diverse protein-protein interactions. Ankyrin repeats are known to be involved in a wide range of cellular processes, including cellular signaling, protein targeting, and protein stability.
Ankyrin repeats are characterized by a helix-loop-helix structure, where each repeat typically consists of two α-helices separated by a β-hairpin loop. The number of repeats in an ANK domain can vary from as few as two to as many as seven or more. The structure of the ANK repeat allows it to form a concave surface that can interact with a variety of partner proteins, such as other ANK repeat-containing proteins or non-ANK repeat proteins.
The functional versatility of ANK repeats lies in their ability to engage in specific and transient interactions with target proteins. These interactions are generally facilitated by the exposed surface residues on the concave side of the ANK repeat. Through these interactions, ANK repeat-containing proteins can participate in various biological processes, including intracellular signaling pathways, DNA binding, cytoskeletal organization, and cellular transport.
Overall, ANK repeats serve as a fundamental building block of protein-protein interactions, enabling the assembly of multi-protein complexes and facilitating the integration of multiple signaling pathways within a cell. Their structural flexibility and diverse functions make ANK repeat-containing proteins critically important for the regulation of cellular processes and understanding various aspects of cellular biology.
Common Misspellings for ANK REPEAT
- znk repeat
- snk repeat
- wnk repeat
- qnk repeat
- abk repeat
- amk repeat
- ajk repeat
- ahk repeat
- anj repeat
- anm repeat
- anl repeat
- ano repeat
- ani repeat
- ank eepeat
- ank depeat
- ank fepeat
- ank tepeat
- ank 5epeat
- ank 4epeat
- ank rwpeat
Etymology of ANK REPEAT
The term "ANK repeat" is derived from two separate origins - "ANK" and "repeat".
1. ANK: ANK is an abbreviation for the term "Ankyrin". Ankyrins are a family of proteins that play a crucial role in cellular stability and organization. They are involved in various biological processes such as neuronal development, cell signaling, and membrane organization.
2. Repeat: In molecular biology, the term "repeat" refers to a particular sequence or motif that occurs multiple times in a protein or DNA sequence. These repeats can have structural or functional significance within a protein.
Therefore, an "ANK repeat" refers to a specific type of repeat motif found in the Ankyrin protein family. ANK repeats consist of approximately 33 amino acids forming a helix-loop-helix structure and are responsible for protein-protein interactions.
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