AOLIGO Meaning and
Definition
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AOLIGO is a term that is commonly used to refer to a type of oligonucleotide molecule that contains a modified form of adenosine, known as 2'-O-alkylated adenosine. Oligonucleotides are short sequences of nucleotides that are composed of sugars, phosphate groups, and nitrogenous bases, and they play a crucial role in many biological processes, particularly in molecular biology and genetics.
The modification of adenosine in AOLIGO involves the addition of an alkyl group at the 2'-position of the sugar moiety. This chemical alteration can have significant effects on the properties of the oligonucleotide, allowing for improved stability, hybridization efficiency, and target specificity. AOLIGO molecules can be synthesized using various chemical methods and are often employed in research and clinical applications as gene regulation tools, particularly in the field of antisense therapy.
The use of AOLIGO in medicine has gained significant attention due to its potential therapeutic applications. 2'-O-alkylated adenosine modifications can enhance the stability of AOLIGO molecules, allowing them to resist enzymatic degradation and enabling prolonged exposure to targeted messenger RNA (mRNA). This property makes AOLIGO a promising candidate for the development of drugs that can selectively inhibit the expression of disease-causing genes.
Overall, AOLIGO refers to a modified form of oligonucleotide containing 2'-O-alkylated adenosine, which exhibits improved stability, hybridization efficiency, and target specificity. Its utility in molecular biology and potential use in medical applications make AOLIGO an important term in the scientific community.
Common Misspellings for AOLIGO
- zoligo
- soligo
- woligo
- qoligo
- ailigo
- akligo
- alligo
- apligo
- a0ligo
- a9ligo
- aokigo
- aopigo
- aooigo
- aolugo
- aoljgo
- aolkgo
- aologo
- aol9go
- aol8go
- aolifo
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