ATP METHIONINE S ADENOSYLTRANSFERASE Meaning and
Definition
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ATP Methionine S Adenosyltransferase (MAT) is an enzyme that plays a crucial role in the biosynthesis of S-adenosylmethionine (SAM), an essential molecule involved in numerous biochemical reactions in living organisms. SAM serves as a methyl group donor for methylation reactions, which are critical for processes such as DNA and protein methylation.
MAT is responsible for catalyzing the transfer of an adenosyl group from ATP (adenosine triphosphate) to L-methionine, resulting in the formation of SAM. This reaction involves the hydrolysis of ATP to adenosine diphosphate (ADP) and inorganic phosphate (Pi). As a result, MAT acts as a key regulator in determining the intracellular concentration of SAM, which is tightly regulated due to its important role in cellular metabolism.
MAT is found in various cell types and is particularly abundant in the liver. It exists as a heterotetramer composed of two different subunits, alpha and beta. The alpha subunit is responsible for binding ATP and methionine, while the beta subunit contributes to the catalytic activity of the enzyme.
The activity of MAT can be influenced by various factors, including cellular conditions, hormonal regulation, and post-translational modifications. Dysregulation of MAT activity has been linked to various diseases, including liver disorders, neurodevelopmental disorders, and cancer. Therefore, understanding the function and regulation of ATP Methionine S Adenosyltransferase is important for elucidating its role in cellular processes and potentially developing therapeutic strategies.
Common Misspellings for ATP METHIONINE S ADENOSYLTRANSFERASE
- ztp methionine s adenosyltransferase
- stp methionine s adenosyltransferase
- wtp methionine s adenosyltransferase
- qtp methionine s adenosyltransferase
- arp methionine s adenosyltransferase
- afp methionine s adenosyltransferase
- agp methionine s adenosyltransferase
- ayp methionine s adenosyltransferase
- a6p methionine s adenosyltransferase
- a5p methionine s adenosyltransferase
- ato methionine s adenosyltransferase
- atl methionine s adenosyltransferase
- at- methionine s adenosyltransferase
- at0 methionine s adenosyltransferase
- atp nethionine s adenosyltransferase
- atp kethionine s adenosyltransferase
- atp jethionine s adenosyltransferase
- atp mwthionine s adenosyltransferase
- atp msthionine s adenosyltransferase
- atp mdthionine s adenosyltransferase
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