BERGAPTEN Meaning and
Definition
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Bergapten is a chemical compound belonging to a group of naturally occurring organic compounds called coumarins. Chemically, it is also known as 5-methoxypsoralen, derived from its structure consisting of a psoralen backbone with an additional methoxy group attached to the fifth carbon atom.
Bergapten is abundantly found in various plants such as bergamot, figs, and celery, as well as in certain essential oils. It is often present in the outer layer of fruits or vegetables, contributing to their characteristic aroma and flavor.
In the field of medicine, bergapten has shown promising applications due to its photosensitizing properties. When exposed to ultraviolet (UV) radiation, bergapten becomes activated and forms covalent bonds with DNA, interfering with the replication and transcription processes. This property has been harnessed in the treatment of skin disorders like psoriasis and vitiligo.
However, the photosensitizing nature of bergapten can also lead to adverse effects, making it a concern in certain contexts. It has been associated with an increased risk of phototoxic reactions or sunburn when applied topically or ingested in high doses. Therefore, precautions must be taken to avoid excessive exposure to sunlight or ultraviolet radiation while using products containing bergapten.
In summary, bergapten is a naturally occurring compound found in plants that possess photosensitizing properties. Its ability to interact with UV radiation has been utilized in medical treatments but should be used with caution due to possible adverse effects.
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A camphor-like substance obtained from the oil of bergamot.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for BERGAPTEN
- vergapten
- nergapten
- hergapten
- gergapten
- bwrgapten
- bsrgapten
- bdrgapten
- brrgapten
- b4rgapten
- b3rgapten
- beegapten
- bedgapten
- befgapten
- betgapten
- be5gapten
- be4gapten
- berfapten
- bervapten
- berbapten
- berhapten
Etymology of BERGAPTEN
The word "bergapten" is derived from the German word "Bergapten" or "Bergaptin". This term was coined by German chemist Ernst Schulz in 1937 when he isolated and identified the compound from bergamot oil. The term "bergapten" is a combination of "berg" (referring to Bergamot) and "apten", derived from "apt", which means "fit" in Latin, referring to the compound being fit for use in chemical or medicinal applications.
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