Chinese hamster ovary cell (CHO cell) is a term used in biology and medicine to describe a specific type of small, rodent-like cells that are derived from the ovaries of Chinese hamsters (Cricetulus griseus). These cells are commonly used in laboratory research and biotechnology, particularly in the field of genetic engineering and the production of therapeutic proteins.
CHO cells are highly valued for their ability to produce large amounts of proteins, making them a popular choice for the industrial production of biopharmaceuticals. They have been extensively studied and engineered to optimize their protein expression capabilities. These cells possess several advantageous characteristics, such as rapid growth, easy cultivation, and high protein production capacity, all of which contribute to their widespread use in the manufacturing process of various therapeutic proteins, including insulin, growth hormones, and monoclonal antibodies.
The name "Chinese hamster ovary cell" refers to the origin of these cells, as they are derived from the ovarian tissues of Chinese hamsters. They are mammalian cells, meaning that they have similar biological and biochemical properties to human cells, making them suitable for studying the expression, function, and regulation of various genes involved in disease processes and drug development.
In summary, Chinese hamster ovary cells (CHO cells) are a type of mammalian cells cultivated in laboratories for their high protein production capabilities. They have become an indispensable tool in biopharmaceutical research and manufacturing, enabling the development of numerous lifesaving drugs and therapies.
