How Do You Spell DIETHYLBARBITURIC ACID?

1. Diethylbarbituric acid is a chemical compound known under the systematic name 5,5-Diethyl-1,3-diazinane-2,4,6-trione. It belongs to the class of barbituric acid derivatives, which are organic compounds widely used as sedatives, hypnotics, and anticonvulsants.

   Diethylbarbituric acid is a white crystalline solid that is sparingly soluble in water. It is primarily synthesized through the reaction of ethyl acetoacetate with urea, followed by an acid-catalyzed ring closure. It appears as a therapeutic intermediate in the synthesis of various barbiturate drugs, most notably phenobarbital, a medication used for the treatment of epilepsy, seizures, and anxiety.

   The compound's therapeutic effects arise due to its ability to bind to and modulate the activity of gamma-aminobutyric acid (GABA) receptors in the central nervous system. This results in the enhancement of inhibitory neurotransmission, leading to sedation, hypnosis, and anticonvulsant effects.

   The pharmacokinetics of diethylbarbituric acid involve rapid absorption upon oral administration and metabolization in the liver. The compound is primarily eliminated through renal excretion as inactive metabolites.

   Overall, diethylbarbituric acid holds significant importance in the field of medicine due to its role as an intermediate in the synthesis of potent barbiturate drugs with diverse therapeutic applications.

2. Diethylmalonyl urea, malo-urea, a ureide derived from diethylmalonic acid, veronal; a white crystalline powder of slightly bitter taste, soluble in 150 parts of water; hypnotic in doses of gr. 5-15 (0.3-1.0).

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for DIETHYLBARBITURIC ACID

The word "diethylbarbituric acid" is derived from its chemical structure and composition.

"Diethyl" is a prefix that indicates the presence of two ethyl groups (-C2H5) in the compound.

"Barbituric acid" is a compound that was first synthesized by Adolf von Baeyer in 1864. The term "barbituric" refers to the central core structure of the compound, which is the barbiturate skeleton. The name "barbiturate" was coined by von Baeyer and derived from the name of his friend and collaborator, the chemist, Johann Friedrich Wilhelm Adolf von Barbier.

So, the term "diethylbarbituric acid" signifies that two ethyl groups are attached to the barbituric acid molecule.