HISTIDINOLPHOSPHATASE Meaning and
Definition
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Histidinolphosphatase is an enzyme that is involved in the metabolism of histidine, an essential amino acid. Also known as histidine acid phosphatase or histidase, histidinolphosphatase plays a crucial role in the breakdown of histidine to a molecule called urocanic acid. This enzyme acts on the phosphorylated form of histidine, known as histidyl phosphate, and catalyzes the removal of a phosphate group to produce histidine and inorganic phosphate.
Histidinolphosphatase is found in various organisms including bacteria, plants, and animals, and its activity levels can vary depending on the tissue or organism in which it is present. In humans, this enzyme is particularly abundant in the liver and kidney.
The function of histidinolphosphatase is important for maintaining histidine homeostasis in the body. It is a key step in the histidine degradation pathway, which allows for the recycling and utilization of histidine residues. This enzyme's activity is tightly regulated, as imbalances in histidine metabolism can lead to various disorders. Deficiencies in histidinolphosphatase activity have been associated with histidinemia, a rare genetic disorder characterized by high levels of histidine in the blood and urine.
Overall, histidinolphosphatase is a vital enzyme involved in the metabolism of histidine, contributing to the proper recycling and utilization of histidine residues in various organisms.
Common Misspellings for HISTIDINOLPHOSPHATASE
- gistidinolphosphatase
- bistidinolphosphatase
- nistidinolphosphatase
- jistidinolphosphatase
- uistidinolphosphatase
- yistidinolphosphatase
- hustidinolphosphatase
- hjstidinolphosphatase
- hkstidinolphosphatase
- hostidinolphosphatase
- h9stidinolphosphatase
- h8stidinolphosphatase
- hiatidinolphosphatase
- hiztidinolphosphatase
- hixtidinolphosphatase
- hidtidinolphosphatase
- hietidinolphosphatase
- hiwtidinolphosphatase
- hisridinolphosphatase
- hisfidinolphosphatase
Etymology of HISTIDINOLPHOSPHATASE
The word "Histidinolphosphatase" is composed of several elements:
1. "Histidinol": This part comes from the amino acid "histidinol", which is a derivative of histidine. The term "histidinol" originated from the combination of "histidine" and the suffix "-inol", which indicates an alcohol derivative.
2. "Phosphatase": This portion refers to a class of enzymes called phosphatases. The term "phosphatase" comes from the joining of the word "phosphate", which refers to a chemical compound containing phosphorus, and the suffix "-ase", which denotes an enzyme.
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