How Do You Spell VITAMIN D RESISTANT RICKETS?

Pronunciation: [vˈɪtəmɪn dˈiː ɹɪsˈɪstənt ɹˈɪkɪts] (IPA)

Vitamin D Resistant Rickets is a medical condition that affects bone development in children. The pronunciation of the word can be illustrated with IPA phonetic transcription, where "Vitamin" is pronounced as /ˈvɪtəmɪn/, "D" as /diː/, "Resistant" as /rɪˈzɪstənt/ and "Rickets" as /ˈrɪk.ɪts/. The disease is caused by a genetic mutation that prevents the body from properly absorbing vitamin D, which is essential for healthy bones. Symptoms may include bowed legs, a curved spine, and stunted growth. Early detection is key to preventing complications.

Meaning and Definition
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VITAMIN D RESISTANT RICKETS Meaning and Definition

  1. Vitamin D resistant rickets is a rare inherited disorder characterized by a resistance to the effects or actions of vitamin D in the body. Rickets is a condition that affects the bones, causing them to become soft, weak, and susceptible to deformation. It is typically caused by a deficiency in vitamin D, which plays a vital role in the absorption of calcium and phosphorus from the diet and their regulation in the body.

    In the case of vitamin D resistant rickets, individuals have a genetic mutation that impairs the function or production of the vitamin D receptor (VDR) present in cells throughout the body. The VDR is responsible for binding to vitamin D and initiating the actions necessary for the regulation of calcium and phosphorus metabolism. Consequently, individuals with this condition are unable to properly absorb or utilize vitamin D, leading to low levels of calcium and phosphorus in the blood.

    The symptoms of vitamin D resistant rickets typically manifest during childhood and may include delayed growth and development, bone deformities (such as bowlegs or knock-knees), muscle weakness, and fractures. Treatment for this condition involves high doses of calcium and phosphorus supplements to help maintain normal blood levels and support proper bone formation. Additionally, synthetic analogs of vitamin D that do not rely on the VDR may be utilized to compensate for the receptor dysfunction. Regular monitoring and supportive care by healthcare professionals specializing in metabolic bone disorders are crucial for individuals with vitamin D resistant rickets to ensure optimal bone health and reduce complications.

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Correct spelling for Vitamin D Resistant Rickets
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