GLYCOPROTEIN SIALYLTRANSFERASE Meaning and
Definition
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Glycoprotein sialyltransferase is an enzyme that catalyzes the transfer of sialic acid residues to glycoproteins. Sialic acid is a nine-carbon sugar that is often found at the terminal positions of sugar chains attached to proteins and lipids on cell surfaces. This enzyme plays a crucial role in the biosynthesis of sialylated glycoproteins, which are involved in various important biological processes.
Glycoprotein sialyltransferase belongs to the family of glycosyltransferases, which are enzymes that transfer sugar residues from nucleotide sugars to specific acceptor molecules. Specifically, glycoprotein sialyltransferase transfers sialic acid from cytidine monophosphate (CMP)-sialic acid to the terminal position of sugar chains on glycoproteins.
The addition of sialic acid residues to glycoproteins can have significant effects on their structure, stability, and function. Sialylation plays a crucial role in modulating cell-cell interactions, cell signaling, immune responses, and other biological processes. It is involved in the recognition and binding of cells, viruses, and pathogens, as well as the regulation of cellular processes such as proliferation, differentiation, and apoptosis.
Dysregulation or deficiency of glycoprotein sialyltransferase can have severe consequences on various physiological and pathological processes, including immune disorders, cancer metastasis, and certain genetic disorders. Therefore, understanding the role and function of this enzyme is vital for elucidating the molecular mechanisms underlying these processes and developing therapeutic strategies targeting glycoprotein sialylation.
Common Misspellings for GLYCOPROTEIN SIALYLTRANSFERASE
- flycoprotein sialyltransferase
- vlycoprotein sialyltransferase
- blycoprotein sialyltransferase
- hlycoprotein sialyltransferase
- ylycoprotein sialyltransferase
- tlycoprotein sialyltransferase
- gkycoprotein sialyltransferase
- gpycoprotein sialyltransferase
- goycoprotein sialyltransferase
- gltcoprotein sialyltransferase
- glgcoprotein sialyltransferase
- glhcoprotein sialyltransferase
- glucoprotein sialyltransferase
- gl7coprotein sialyltransferase
- gl6coprotein sialyltransferase
- glyxoprotein sialyltransferase
- glyvoprotein sialyltransferase
- glyfoprotein sialyltransferase
- glydoprotein sialyltransferase
- glyciprotein sialyltransferase
Etymology of GLYCOPROTEIN SIALYLTRANSFERASE
The word "sialyltransferase" is derived from a combination of "sialo-" and "transferase". "Sialo" comes from the Greek word "sialon", meaning saliva, while "transferase" originates from the Latin word "transferre", meaning "to transfer".
Additionally, "glycoprotein" is a compound word formed by combining "glyco-" and "protein". "Glyco" stems from the Greek word "glykys", meaning sweet or sugar, while "protein" comes from the Greek word "proteios", meaning primary or first rank. Therefore, "glycoprotein" refers to a type of protein molecule that contains one or more attached sugars or carbohydrates.
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